Selected publications (last 3 years), C: corresponding author
Seferna K, Svaton M, Rennerova A, Skotnicova A, Reznickova L, Valova T, Sedlacek P, Riha P, Formankova R, Keslova P, Sramkova L, Stary J, Zuna J, Kolenova A, Salek C, Trka J, Fronkova E (C).: NGS-MRD negativity in post-HSCT ALL spares unnecessary therapeutic interventions triggered by borderline qPCR results without an increase in relapse risk. Hemasphere 2025 Apr 8;9(4):e70124. (D1)
Stoltze U, Junk SV, Byrjalsen A, Cavé H, Cazzaniga G, Elitzur S, Fronkova E, Hjalgrim LL, Kuiper RP, Lundgren L, Mescher M, Mikkelsen T, Pastorczak A, Strullu M, Trka J, Wadt K, Izraeli S, Borkhardt A, Schmiegelow K.: Overt and covert genetic causes of pediatric acute lymphoblastic leukemia. Leukemia 2025 May;39(5):1031-1045. doi: 10.1038/s41375-025-02535-4. (D1)
Svaton M, Skotnicova A, Reznickova L, Rennerova A, Valova T, Kotrova M, van der Velden VHJ, Brüggemann M, Darzentas N, Langerak AW, Zuna J, Stary J, Trka J, Fronkova E.(C): NGS better discriminates true MRD positivity for the risk stratification of childhood ALL treated on MRD-based protocol. Blood 2023,141(5),529-533. DOI:10.1182/blood.2022017003. (D1)
Kalinova M, Mrhalova M, Kabickova E, Svaton M, Skotnicova A, Prouzova Z, Krenova Z, Kolenova A, Divoka M, Fronkova E (C), Kodet R.: Molecular Screening in Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma: Anaplastic Lymphoma Kinase Analysis, Next-Generation Sequencing Fusion Gene Detection, and T-Cell Receptor Immunoprofiling. Mod Pathol 2024 Mar;37(3):100428. doi: 10.1016/j.modpat.2024.100428. Epub 2024 Jan 23.(D1)
van der Velden VHJ, Dombrink I, Alten J, Cazzaniga G, Clappier E, Drandi D, Eckert C, Fronkova E, Hancock J, Kotrova M, Kraemer R, Montonen M, Pfeifer H, Pott C, Raff T, Trautmann H, Cavé H, Schäfer BW, van Dongen JJM, Trka J, Brüggemann M; EuroMRD Consortium: Analysis of measurable residual disease by IG/TR gene rearrangements: quality assurance and updated EuroMRD guidelines. Leukemia 2024 Jun;38(6):1315-1322. doi: 10.1038/s41375-024-02272-0. (D1)
Haematopoiesis and its disorders (malignancies, bone marrow failure, immunodeficiencies and immune dysregulation), recombination of immunoglobulin (Ig) and T-cell receptor (TCR) genes, minimal residual disease (MRD) in lymphoid lineage malignancies, next generation sequencing (NGS), multiomics
