Recovery from Autism after Successful Surgery for a Benign Brain Tumor Associated with Epilepsy.

Hrdlička, M., Kudr, M., Kršek, P., Tichý, M., Kynčl, M., Zámečník, J., Mohaplová, M., Dudová, I. Journal of Autism and Developmental Disorders. 2019 Feb 19. doi: 10.1007/s10803-019-03935-z. [Epub ahead of print]. IF: 3.476

prof. MUDr. Michal Hrdlička, CSc.

prof. MUDr. Michal Hrdlička, CSc., Department of Paediatric Psychiatry


A rare example of syndromic autism is autism spectrum disorder (ASD) in children with brain tumors. The case reports on this association are few and mostly involve autism and cerebellar pilocytic astrocytoma (Omar et al. ; Adachi et al. ; Minhas et al. ), right temporal ganglioglioma (Mikati et al. ), and mesial temporal oligodendroglioma (Hoon and Reiss ). The majority of the described cases underwent neurosurgery for removal of the brain tumor (Adachi et al. ; Minhas et al. ; Mikati et al. ; Hoon and Reiss ). Following surgery, autism remained unchanged (Adachi et al. ), was minimally or mildly improved (Hoon and Reiss ; Mikati et al. ), or autism improvement was not specified (Minhas et al. ).

Case Report

A 3 year 9 month old boy was referred to the child psychiatry department for a diagnostic evaluation of neurodevelopmental delay with suspicion of autism. Speech development was significantly delayed; at the time of...

Published: 15. 5. 2019 / Last update: 16. 5. 2019 / Responsible person: Mgr. Ing. Tereza Kůstková