Pharmacology and Toxicology

Accreditation valid until: 11. 12. 2029

Chairman of the Subject Area Board:
prof. MUDr. Ondřej Slanař, Ph.D.
Institute of Pharmacology
First Faculty of Medicine
Charles University and General University Hospital
Albertov 4
128 00  Prague 2
phone: +420 224 968 146
e-mail: @email

Members of the Subject Area Board

Characteristics of the study programme

Pharmacology and toxicology are sciences that study the mechanisms of mutual interactions of substances and medicinal preparations with biologic systems and observe their both favourable and adverse impact on the organism. The final goal is the use of this knowledge in prevention, diagnosis and treatment of human and veterinary conditions.

A great advantage of the study of pharmacology and toxicology is the close interconnection of the theoretic field with all clinical specialties that perform therapy, prevention and diagnosis. The study programme in Pharmacology and Toxicology is therefore suitable not only for those interested in experimental research but also for those seeking their prospective careers in clinical work. The main bias of the study programme, nevertheless, is experimental, at both the pre-clinical and clinical level.

The goal of the doctoral programme Pharmacology and Toxicology is training specialists with deep knowledge in the areas of clinical as well experimental pharmacology and toxicology. This envelops knowledge of wide areas of pharmacokinetics, pharmacodynamics, effects and toxicity of medications, including the knowledge of properties of particular forms of medicinal preparations.

Requirements during the study

Specific contents of the doctoral studies are provided for each student by an ISP. Obligatorily, it contains passing at least two subjects provided by any SAB within the Co-ordinating Council of DSPB. It is recommended that at least one of the subjects passed is provided by the SAB of Pharmacology and toxicology.

Part of the ISP is also the language examination in English (examination at the Department of Languages, Second Faculty of Medicine CU, state language examination or an internationally recognized examination, e.g. TOEFL, Cambridge Certificate).

The ISP includes continuous publishing activity and presentation of the results at national and international scientific conferences. Also possible / recommendable is the students’ participation in undergraduate tuition (practical classes).

Requirements for internships

A recommended part of study obligations in studies is taking a study placement abroad. Also welcome is another form of the student’s direct participation in international co-operation, e.g. in an international creative project with results published or presented abroad, etc.,

Listed courses


Requirements for the SDE

The SDE usually takes place in the 3rd year of studies. The requisites of admission for the examination are:

- credits from at least two subjects passed;
- literature search for the topic (20-30 pages) or an own scientific publication in a reviewed journal (synoptic articles are admitted as well).

The SDE is held in such an extent that is in keeping with the study programme of the SAB. Its objective is checking the student’s way of scientific thought, i.e. his/her ability of comprehension of the nature of the problem, including the ability of conceiving own ways of solution to the given problems. At the examination, the students are supposed to prove their knowledge of their chosen field to the full extent of the undergraduate level but also the knowledge of trends in research and modern methodology of recent biomedicine as applied to the topic area of his/her dissertation thesis. The examination consists of discussion of the passed subjects completed with credits, discussion of the literature search submitted or the applicant’s own publication, and answering three questions drawn at random. The examining questions for pharmacology and toxicology are displayed at the pages of the SAB, together with the recommended literature.

Examination topics for the SDE
Recommended literature
Publication activity requirements

At least two original publications in journals with IF that pertain to the topic of the thesis and together have a total impact factor not smaller than 1.0. At least in one publication, the doctorand must be the first author.

Defence requirements
At least two original publications in a journal with an IF pertaining to the topic of the thesis, which together have the total impact factor not lower than 1.0. In at least one of them, the doctorand should be shown as the first author.

The SAB requires a Summary of the Dissertation.

Created: 19. 5. 2021 / Modified: 9. 6. 2021 / Responsible person: ThDr. Jitka Sýkorová, Ph.D.