Charvat J, Chlumsky J, Szabo M, Zakovicova E, Zamrazil V. Diabetes Res Clin Pract. 2010 Sep;89(3):239–42. Epub 2010 May 31. IF: 2.160
Abstract:
OBJECTIVES: To evaluate the association of masked hypertension (MH) in treated type 2 diabetic patients without history of cardiovascular disease with carotid artery target organ damage. METHODS: Sixty-four type 2 diabetic patients treated for hypertension with office BP below 140/90 mm Hg were examined by 24-h BP monitoring and carotid sonography. MH was diagnosed if daily mean ambulatory BP was >or= 135/85 mm Hg. The association of MH with carotid artery parameters was evaluated. RESULTS: The average age of patients was 62 ± 5 years. Twenty-four patients had MH (37.5 %). Carotid artery IMT was 0.74 ± 0.08 mm in patients with MH and 0.69 ± 0.06 mm without MH (p = 0.03). The distensibility of common carotid artery was 0.24 ± 0.07 mmHg–1 in patients with MH and 0.29 ± 0.1mm Hg–1 without MH (p = 0.14). After adjustment for age, gender, smoking, duration of diabetes, BMI and clinic blood pressure (BP) values the association of MH with carotid artery IMT was sustained. CONCLUSION: Masked hypertension in treated type 2 diabetic patients is associated with carotid artery IMT.
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